Some bodybuilders and athletes use trenbolone for its muscle-building and otherwise performance-enhancing effects. [ citation needed ] Such use is illegal in the United States and many other countries. The DEA classifies trenbolone as a Schedule III controlled substance under the Controlled Substances Act .  Trenbolone is classified as a Schedule 4 drug in Canada  and a class C drug with no penalty for personal use or possession in the United Kingdom .  Use or possession of steroids without a prescription is a crime in Australia .  The infamous "duchess" cocktail administered to Russian athletes at the Sochi Winter Olympics consisted of oxandrolone , metenolone , and trenbolone. 
Drugs such as Nolvedex bind to the oestrogen receptors , therefore reducing the effects of the heightened oestrogen in the body. Such drugs do nothing to reduce the amount of oestrogen in the body; they merely reduce its effects via competition for the receptors . If the user wishes to reduce the amount of oestrogen they should look to drugs such as proviron and anastrozole , which are known as anti-aromatases - . they lower the conversion of the steroid to oestrogen and therefore reduces the overall amount of oestrogen present.
Dianabol is also capable of interaction with the enzyme aromatase resulting in the possibility of estrogenic side effects. Gynecomastia may become apparent even very early into a cycle, so the user must always ensure that they have the necessary drugs to treat the condition at the earliest possible opportunity. A Selective Estrogen Modulator (SERM) such as Tamoxifen (brand name Nolvadex) is usually used in these instances, perhaps with the addition of an anti-estrogen such as Proviron or Arimidex which will help hinder further estrogenic conversion. (For more information see the article Combating Oestrogens & Progesterone ).